Metabolyn 3
HK$595.0 HK$523.6
產品描述：
Reverse the red flags — boost longevity · protect blood vessels · balance the three highs.* Formulated for adults managing the three highs, balancing them from the metabolic root while activating longevity. 1 box / 60 capsules
產品資料：
如有長期服用藥物，建議每 2–3 個月定期身體檢查及跟進相關指數
How to use:
- 每日 2 粒：餐前食用，配溫水送服
- 與西藥並用：建議相隔約 2 小時，以減少互相影響吸收
- 長期服用追蹤：如同時服用薄血藥，建議每 2–3 個月定期身體檢查跟進相關指數
使用程序：餐前 2 粒（早 / 晚分次或一次性服用）
Product Details
Activate the metabolic longevity axis — balance glucose, lipids and pressure
dr.he was born from reverse thinking, built on over 21 years of private research in naturopathy and biochemistry by Dr. Eugene He. The original formula was created to address his own health concerns. With metabolic health as its core — because metabolism underpins energy, resilience, physique and long-term vitality — the work eventually gave rise to the Metabolyn range. The brand strikes a deliberate balance between natural wisdom and rigorous science, anchored in genuine results rather than commercial gain. Its mission is to enhance quality of life and vitality — true longevity is not merely a longer life, but ensuring every year is full of energy and meaning.
Why Choose METABOLYN 3 Metabolic Balance Capsules?
dr.he METABOLYN 3 Metabolic Balance Capsules are designed for consumers pursuing high-quality wellness and healthy living. Positioning: activate the metabolic longevity axis — balance glucose, lipids and pressure. dr.he is rooted in Singapore, carrying forward local ingredient sourcing and manufacturing traditions. The following breaks down — from real-world use experience, formulation strengths and lifestyle context — why METABOLYN 3 Metabolic Balance Capsules deserve a place in your daily routine.
Simultaneously activates SIRT1 (longevity protein) and AMPK (cellular energy sensor) — two longevity axes
Co-regulates blood lipids, blood glucose and blood pressure from the metabolic root, addressing all three high-risk indicators in one capsule — no need to stack three or four separate supplements.
Patented Care300® Mango Extract + ABG10+ Aged Black Garlic (dual patented actives)
Clinical evidence: SIRT1 activity +30%, SOD activity +50% — backed by third-party data, not manufacturer self-claims.
Methylated active B-complex (B2 / B6 / B9 / B12)
No hepatic conversion required — directly absorbed and utilised by the body. Suitable for those with MTHFR gene variants and older adults with reduced metabolic capacity.
Nattokinase: fibrinolytic activity four times that of plasmin
Reduces fibrinogen by 9%, Factor VII by 14% and Factor VIII by 17% (Hsia 2009), helping maintain vascular flow and lowering thrombotic risk.
Natural ingredients — no caffeine, stimulants or habit-forming substances
Suitable for long-term use without affecting prescription medication, and can be taken alongside diabetes drugs, blood thinners and other chronic prescriptions (suggested gap of 2 hours).
Overall, dr.he METABOLYN 3 Metabolic Balance Capsules are tightly controlled across formula, origin and user experience. MI MING MART curates this product because its overall standing in the category is genuinely standout — bringing Hong Kong consumers a higher-bar, dependable choice.
Clinical Evidence
BenefitsBenefits+
AdvantagesProduct Advantages+
Key IngredientsCore Ingredients+
METABOLYN™ 3 Complex
- Action: 950 mg / day — complementary mechanisms supporting metabolic and cardiovascular function
- Details: Built from four standardised actives — Care300® Mango Extract, Aged Black Garlic ABG10+, Nattokinase and Indian Gooseberry (Amla) — addressing metabolic signalling, antioxidant defence, blood-pressure regulation and fibrinolysis simultaneously.
Care300® Standardized Mango Extract
- Action: Dual activation of SIRT1 + AMPK
- Details: Standardised mangiferin extracted from southern India (Tamil Nadu), rich in C-glucosylxanthone. Clinical data show SIRT1 activity +30%; in vitro studies show AMPK activation, improved glucose metabolism, fatty-acid oxidation and mitochondrial biogenesis. SOD activity +50%. Glucose tolerance improved at 4 weeks (Buchwald-Werner 2017, n=75, HOMA index 1.75–5.0).
Aged Black Garlic ABG10+
- Action: Dual regulation of blood pressure and blood lipids
- Details: Made in Spain using the ABG-COOL-Tech™ low-temperature process to stabilise allicin; cell viability >97%, human trial compliance 92%. At 1.25 mg SAC / day: diastolic -4.82 mmHg, systolic -10.2 mmHg (Valls 2022 / Ried 2010). Animal model (30 days): triglycerides -30%, LDL cholesterol -20%, HDL cholesterol +15%, leptin -35%, adiponectin +25% (Amor 2019).
Amla / Emblica officinalis
- Action: Lipid regulation + cardio protection + weight-management metabolism
- Details: 12-week clinical study (Upadya 2019, n=98, BMC Complementary): total cholesterol -24%, triglycerides -34%, LDL -20%, AIP -39%. 90-day study (1000 mg/day): body weight -9.9%, visceral fat -20.8%, BMI -9.4%, total body fat -17.9%, metabolic age -12.4%.
Nattokinase
- Action: Fibrinolytic activity four times that of plasmin — supports vascular flow
- Details: Sourced from Bacillus subtilis var. natto; a Japanese dietary staple for over 1,000 years. 8-week trial (Kim 2008, n=86): systolic -5.55 mmHg, diastolic -2.84 mmHg, renin activity -1.17 ng/mL/h. 3-month trial (Liu 2024, n=178 stable coronary disease): triglycerides, total cholesterol and diastolic pressure achieved maximum reductions, with HDL significantly elevated. After 2 consecutive months (Hsia 2009): fibrinogen -9%, Factor VII -14%, Factor VIII -17%.
Methylated B-Complex
- Action: Direct bioactivity — no hepatic conversion required
- Details: Daily dose: riboflavin (B2) 12.5 mg, B6 20 mg, folate 400 mcg, B12 250 mcg. 8-week clinical study (Yuan 2021, BMC Medicine, Mendelian randomisation): folate-led active B-complex reduces homocysteine by 25%, with an additional 7% from B12.
How to UseHow to Use+
Use CasesWho It’s For+
FAQFAQ+
Can I take this alongside NMNH?
Can I take this while on blood thinners?
Can it be taken with diabetes medication?
Will my readings rebound immediately after stopping?
Can I take it if I have eczema? (formula contains mango extract)
Is it suitable for vegetarians or those sensitive to gluten, soy or nuts?
CautionsCautions+
- ⚠If on long-term medication, schedule a check-up every 2–3 months to track relevant indicators
- ⚠Not a substitute for doctor-prescribed medication; continue any blood thinner / antihypertensive / diabetes prescription as directed by your doctor
- ⚠Those with mango allergy should review the ingredient list carefully and consult a doctor
- ⚠Suggested gap of around 2 hours between this product and prescription medication
- ⚠Continuous use beyond brand-cited trial durations (8–12 weeks) has not been independently evaluated
Features
- Step 1 — 同時激活 SIRT1（長壽蛋白）+ AMPK（細胞能量感測器）兩大延壽軸
從代謝根源同步調控血脂、血糖、血壓。一粒兼顧三高指標，免食三、四種補充劑 - Step 2 — 專利 Care300® 芒果萃取 + ABG10+ 熟成黑蒜（雙專利成分）
臨床實證 SIRT1 活性 +30%、SOD 活性 +50%。第三方數據支持，並非廠商自說自話 - Step 3 — 甲基化活性 B 群（B2 / B6 / B9 / B12）
無需肝臟轉換，可直接被身體吸收利用。適合 MTHFR 基因變異者、代謝較弱長者 - Step 4 — 納豆激酶纖溶活性為纖溶酶的 4 倍
降低纖維蛋白原 9%、第七因子 14%、第八因子 17%。維持血管通暢，降低血栓形成風險 - Step 5 — 天然成分，不含咖啡因 / 興奮劑 / 依賴性物質
適合長期服用，不影響西藥效果。可與糖尿病藥、薄血藥等長期處方並用（建議相隔 2 小時）
主要成份
METABOLYN™ 3 複合配方 (METABOLYN™ 3 Complex)
950mg / 日 — 互補機制支持代謝與心血管功能
由芒果萃取物 Care300®、陳年黑蒜 ABG10+、納豆激酶 nattokinase、
印度醋栗（Amla）四大標準化成分組成，從代謝信號、抗氧化、血壓
調節、纖溶四個面向同時介入。
Care300® 芒果萃取物 (Care300® Standardized Mango Extract)
SIRT1 + AMPK 雙啟動
印度南部 Tamil Nadu 標準化提取的芒果苷，含 C-葡糖苷黃酮（C-glucosylxanthone）。
臨床實證 SIRT1 活性 +30%；體外研究顯示活化 AMPK，提升葡萄糖代謝、
脂肪酸氧化、粒線體合成。SOD 活性 +50%。4 週可改善葡萄糖耐受性
（Buchwald-Werner 2017，n=75，HOMA 指數 1.75–5.0）。
陳年黑蒜 ABG10+ (Aged Black Garlic ABG10+)
血壓 + 血脂雙調節
西班牙製造，ABG-COOL-Tech™ 低溫處理穩定蒜素，細胞存活率 >97%，
人體試驗順從性 92%。1.25mg SAC / 日：舒張壓 -4.82 mmHg、收縮壓
-10.2 mmHg（Valls 2022 / Ried 2010）。動物模型 30 日：三酸甘油脂
-30%、壞膽固醇 -20%、好膽固醇 +15%、瘦素 -35%、脂聯素 +25%
（Amor 2019）。
印度醋栗（Amla） (Amla / Emblica officinalis)
血脂調節 + 心臟保護 + 減重代謝
12 週臨床（Upadya 2019，n=98，BMC Complementary）：總膽固醇 -24%、
三酸甘油脂 -34%、LDL -20%、AIP -39%。90 日（每日 1000mg）：體重
-9.9%、內臟脂肪 -20.8%、BMI -9.4%、全身脂肪 -17.9%、代謝性體年齡
-12.4%。
納豆激酶 (Nattokinase)
纖溶活性為纖溶酶的 4 倍 — 維持血管通暢
源自枯草桿菌納豆亞種；日本傳統飲食超過 1,000 年。8 週臨床（Kim 2008，
n=86）：收縮壓 -5.55 mmHg、舒張壓 -2.84 mmHg、腎素活性 -1.17 ng/mL/h。
3 個月臨床（Liu 2024，n=178 穩定性冠心病）：三酸甘油脂、總膽固醇、
舒張壓達最大降幅，HDL 顯著上升。連續 2 個月（Hsia 2009）：纖維蛋白原
-9%、第七因子 -14%、第八因子 -17%。
甲基化 B 群 (Methylated B-Complex)
直接生物活性，不需肝臟轉換
每日劑量：核黃素（B2）12.5 mg、B6 20 mg、葉酸 400 mcg、B12 250 mcg。
8 週臨床（Yuan 2021，BMC Medicine，孟德爾隨機化）：以葉酸為主的
活性 B 群可使 Hcy -25%，B12 額外 -7%。
Benefit
- 一粒兼顧三高指標，免食三、四種補充劑
- 第三方數據支持，並非廠商自說自話
- 適合 MTHFR 基因變異者、代謝較弱長者
- 維持血管通暢，降低血栓形成風險
- 可與糖尿病藥、薄血藥等長期處方並用（建議相隔 2 小時）
臨床數據摘要：
- SIRT1 活性提升 — 超過 30%（體外 / 動物模型（Care300® 芒果萃取））
- SOD 活性提升 — 約 50%（Care300® 芒果萃取）
- 葡萄糖耐受性改善 — 顯示長期葡萄糖調節能力增強（4 週（Buchwald-Werner 2017，n=75））
- 舒張壓下降（陳年黑蒜 ABG10+） — -4.82 mmHg（特別是男性、基線舒張壓 >75 mmHg）（12 週（Valls 2022））
- 收縮壓下降（陳年黑蒜 ABG10+） — -10.2 mmHg 平均（12 週（Ried 2010））
- 三酸甘油脂下降（印度醋栗 Amla） — -34%（12 週（Upadya 2019，n=98））
- 體重 / 體脂下降（印度醋栗 Amla） — 體重 -9.9%、內臟脂肪 -20.8%（90 日（每日 1000mg，n=40））
- 同型半胱氨酸下降（甲基化 B 群） — -25%（葉酸主力）+ B12 額外 -7%（8 週（Yuan 2021，BMC Medicine））
- 收縮壓 / 舒張壓下降（納豆激酶） — 收縮壓 -5.55 mmHg、舒張壓 -2.84 mmHg（8 週（Kim 2008，n=86））
- 纖維蛋白原 / 凝血因子下降（納豆激酶） — 纖維蛋白原 -9%、第七因子 -14%、第八因子 -17%（2 個月（Hsia 2009，n=45））
注意事項
- 如有長期服用藥物，建議每 2–3 個月定期身體檢查及跟進相關指數
- 不可取代醫生處方藥物；薄血藥 / 降壓藥 / 糖尿藥患者請按醫生指示繼續服用
- 對芒果過敏者請仔細查看成分表並諮詢醫生
- 與西藥服用建議相隔約 2 小時
- 連續服用 (TODO verify long-term safety beyond brand-cited studies — source cites 8–12 週 trials)
Related knowledge
何謂「三高」
指高血壓、高血糖、高血脂三種最常見的慢性疾病。三者環環相扣：高血脂可能導致血管狹窄與血壓升高；血糖代謝紊亂常伴隨脂肪代謝異常。長期控制不佳會增加心肌梗塞、中風、慢性腎臟病、視網膜病變等併發症風險。
SIRT1 與 AMPK 兩大延壽軸
SIRT1 是 NAD+ 依賴的去乙醯酶，負責調控能量恆定、脂質代謝與細胞壓力耐受；AMPK 是能量感測器，透過促進脂肪氧化、葡萄糖攝取與粒線體生合成恢復代謝平衡。兩者互補：AMPK 即時降血糖、燃脂、舒張血管；SIRT1 長期提升胰島素敏感性、保護血管內皮、延緩老化。
同型半胱氨酸（Homocysteine, Hcy）
血液中的一種氨基酸代謝中間產物。正常數值 5–15 μmol/L，過高（>16）會引發氧化應激、損害血管內皮、誘導凝血、形成動脈粥樣硬化斑塊。B9（葉酸）+ B12 是「回收車間」，B6 是「廢棄車間」，缺一不可。本品採用甲基化活性 B 群，可直接被身體利用，臨床實證 8 週可使 Hcy下降 25%（葉酸主力），B12 額外再降 7%。
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Activate the metabolic longevity axis — balance glucose, lipids and pressure
dr.he was born from reverse thinking, built on over 21 years of private research in naturopathy and biochemistry by Dr. Eugene He. The original formula was created to address his own health concerns. With metabolic health as its core — because metabolism underpins energy, resilience, physique and long-term vitality — the work eventually gave rise to the Metabolyn range. The brand strikes a deliberate balance between natural wisdom and rigorous science, anchored in genuine results rather than commercial gain. Its mission is to enhance quality of life and vitality — true longevity is not merely a longer life, but ensuring every year is full of energy and meaning.
Why Choose METABOLYN 3 Metabolic Balance Capsules?
dr.he METABOLYN 3 Metabolic Balance Capsules are designed for consumers pursuing high-quality wellness and healthy living. Positioning: activate the metabolic longevity axis — balance glucose, lipids and pressure. dr.he is rooted in Singapore, carrying forward local ingredient sourcing and manufacturing traditions. The following breaks down — from real-world use experience, formulation strengths and lifestyle context — why METABOLYN 3 Metabolic Balance Capsules deserve a place in your daily routine.
Simultaneously activates SIRT1 (longevity protein) and AMPK (cellular energy sensor) — two longevity axes
Co-regulates blood lipids, blood glucose and blood pressure from the metabolic root, addressing all three high-risk indicators in one capsule — no need to stack three or four separate supplements.
Patented Care300® Mango Extract + ABG10+ Aged Black Garlic (dual patented actives)
Clinical evidence: SIRT1 activity +30%, SOD activity +50% — backed by third-party data, not manufacturer self-claims.
Methylated active B-complex (B2 / B6 / B9 / B12)
No hepatic conversion required — directly absorbed and utilised by the body. Suitable for those with MTHFR gene variants and older adults with reduced metabolic capacity.
Nattokinase: fibrinolytic activity four times that of plasmin
Reduces fibrinogen by 9%, Factor VII by 14% and Factor VIII by 17% (Hsia 2009), helping maintain vascular flow and lowering thrombotic risk.
Natural ingredients — no caffeine, stimulants or habit-forming substances
Suitable for long-term use without affecting prescription medication, and can be taken alongside diabetes drugs, blood thinners and other chronic prescriptions (suggested gap of 2 hours).
Overall, dr.he METABOLYN 3 Metabolic Balance Capsules are tightly controlled across formula, origin and user experience. MI MING MART curates this product because its overall standing in the category is genuinely standout — bringing Hong Kong consumers a higher-bar, dependable choice.
Clinical Evidence
BenefitsBenefits+
AdvantagesProduct Advantages+
Key IngredientsCore Ingredients+
METABOLYN™ 3 Complex
- Action: 950 mg / day — complementary mechanisms supporting metabolic and cardiovascular function
- Details: Built from four standardised actives — Care300® Mango Extract, Aged Black Garlic ABG10+, Nattokinase and Indian Gooseberry (Amla) — addressing metabolic signalling, antioxidant defence, blood-pressure regulation and fibrinolysis simultaneously.
Care300® Standardized Mango Extract
- Action: Dual activation of SIRT1 + AMPK
- Details: Standardised mangiferin extracted from southern India (Tamil Nadu), rich in C-glucosylxanthone. Clinical data show SIRT1 activity +30%; in vitro studies show AMPK activation, improved glucose metabolism, fatty-acid oxidation and mitochondrial biogenesis. SOD activity +50%. Glucose tolerance improved at 4 weeks (Buchwald-Werner 2017, n=75, HOMA index 1.75–5.0).
Aged Black Garlic ABG10+
- Action: Dual regulation of blood pressure and blood lipids
- Details: Made in Spain using the ABG-COOL-Tech™ low-temperature process to stabilise allicin; cell viability >97%, human trial compliance 92%. At 1.25 mg SAC / day: diastolic -4.82 mmHg, systolic -10.2 mmHg (Valls 2022 / Ried 2010). Animal model (30 days): triglycerides -30%, LDL cholesterol -20%, HDL cholesterol +15%, leptin -35%, adiponectin +25% (Amor 2019).
Amla / Emblica officinalis
- Action: Lipid regulation + cardio protection + weight-management metabolism
- Details: 12-week clinical study (Upadya 2019, n=98, BMC Complementary): total cholesterol -24%, triglycerides -34%, LDL -20%, AIP -39%. 90-day study (1000 mg/day): body weight -9.9%, visceral fat -20.8%, BMI -9.4%, total body fat -17.9%, metabolic age -12.4%.
Nattokinase
- Action: Fibrinolytic activity four times that of plasmin — supports vascular flow
- Details: Sourced from Bacillus subtilis var. natto; a Japanese dietary staple for over 1,000 years. 8-week trial (Kim 2008, n=86): systolic -5.55 mmHg, diastolic -2.84 mmHg, renin activity -1.17 ng/mL/h. 3-month trial (Liu 2024, n=178 stable coronary disease): triglycerides, total cholesterol and diastolic pressure achieved maximum reductions, with HDL significantly elevated. After 2 consecutive months (Hsia 2009): fibrinogen -9%, Factor VII -14%, Factor VIII -17%.
Methylated B-Complex
- Action: Direct bioactivity — no hepatic conversion required
- Details: Daily dose: riboflavin (B2) 12.5 mg, B6 20 mg, folate 400 mcg, B12 250 mcg. 8-week clinical study (Yuan 2021, BMC Medicine, Mendelian randomisation): folate-led active B-complex reduces homocysteine by 25%, with an additional 7% from B12.
How to UseHow to Use+
Use CasesWho It’s For+
FAQFAQ+
Can I take this alongside NMNH?
Can I take this while on blood thinners?
Can it be taken with diabetes medication?
Will my readings rebound immediately after stopping?
Can I take it if I have eczema? (formula contains mango extract)
Is it suitable for vegetarians or those sensitive to gluten, soy or nuts?
CautionsCautions+
- ⚠If on long-term medication, schedule a check-up every 2–3 months to track relevant indicators
- ⚠Not a substitute for doctor-prescribed medication; continue any blood thinner / antihypertensive / diabetes prescription as directed by your doctor
- ⚠Those with mango allergy should review the ingredient list carefully and consult a doctor
- ⚠Suggested gap of around 2 hours between this product and prescription medication
- ⚠Continuous use beyond brand-cited trial durations (8–12 weeks) has not been independently evaluated
產品特點
- Step 1 — 同時激活 SIRT1（長壽蛋白）+ AMPK（細胞能量感測器）兩大延壽軸
從代謝根源同步調控血脂、血糖、血壓。一粒兼顧三高指標，免食三、四種補充劑 - Step 2 — 專利 Care300® 芒果萃取 + ABG10+ 熟成黑蒜（雙專利成分）
臨床實證 SIRT1 活性 +30%、SOD 活性 +50%。第三方數據支持，並非廠商自說自話 - Step 3 — 甲基化活性 B 群（B2 / B6 / B9 / B12）
無需肝臟轉換，可直接被身體吸收利用。適合 MTHFR 基因變異者、代謝較弱長者 - Step 4 — 納豆激酶纖溶活性為纖溶酶的 4 倍
降低纖維蛋白原 9%、第七因子 14%、第八因子 17%。維持血管通暢，降低血栓形成風險 - Step 5 — 天然成分，不含咖啡因 / 興奮劑 / 依賴性物質
適合長期服用，不影響西藥效果。可與糖尿病藥、薄血藥等長期處方並用（建議相隔 2 小時）
主要成份
METABOLYN™ 3 複合配方 (METABOLYN™ 3 Complex)
950mg / 日 — 互補機制支持代謝與心血管功能
由芒果萃取物 Care300®、陳年黑蒜 ABG10+、納豆激酶 nattokinase、
印度醋栗（Amla）四大標準化成分組成，從代謝信號、抗氧化、血壓
調節、纖溶四個面向同時介入。
Care300® 芒果萃取物 (Care300® Standardized Mango Extract)
SIRT1 + AMPK 雙啟動
印度南部 Tamil Nadu 標準化提取的芒果苷，含 C-葡糖苷黃酮（C-glucosylxanthone）。
臨床實證 SIRT1 活性 +30%；體外研究顯示活化 AMPK，提升葡萄糖代謝、
脂肪酸氧化、粒線體合成。SOD 活性 +50%。4 週可改善葡萄糖耐受性
（Buchwald-Werner 2017，n=75，HOMA 指數 1.75–5.0）。
陳年黑蒜 ABG10+ (Aged Black Garlic ABG10+)
血壓 + 血脂雙調節
西班牙製造，ABG-COOL-Tech™ 低溫處理穩定蒜素，細胞存活率 >97%，
人體試驗順從性 92%。1.25mg SAC / 日：舒張壓 -4.82 mmHg、收縮壓
-10.2 mmHg（Valls 2022 / Ried 2010）。動物模型 30 日：三酸甘油脂
-30%、壞膽固醇 -20%、好膽固醇 +15%、瘦素 -35%、脂聯素 +25%
（Amor 2019）。
印度醋栗（Amla） (Amla / Emblica officinalis)
血脂調節 + 心臟保護 + 減重代謝
12 週臨床（Upadya 2019，n=98，BMC Complementary）：總膽固醇 -24%、
三酸甘油脂 -34%、LDL -20%、AIP -39%。90 日（每日 1000mg）：體重
-9.9%、內臟脂肪 -20.8%、BMI -9.4%、全身脂肪 -17.9%、代謝性體年齡
-12.4%。
納豆激酶 (Nattokinase)
纖溶活性為纖溶酶的 4 倍 — 維持血管通暢
源自枯草桿菌納豆亞種；日本傳統飲食超過 1,000 年。8 週臨床（Kim 2008，
n=86）：收縮壓 -5.55 mmHg、舒張壓 -2.84 mmHg、腎素活性 -1.17 ng/mL/h。
3 個月臨床（Liu 2024，n=178 穩定性冠心病）：三酸甘油脂、總膽固醇、
舒張壓達最大降幅，HDL 顯著上升。連續 2 個月（Hsia 2009）：纖維蛋白原
-9%、第七因子 -14%、第八因子 -17%。
甲基化 B 群 (Methylated B-Complex)
直接生物活性，不需肝臟轉換
每日劑量：核黃素（B2）12.5 mg、B6 20 mg、葉酸 400 mcg、B12 250 mcg。
8 週臨床（Yuan 2021，BMC Medicine，孟德爾隨機化）：以葉酸為主的
活性 B 群可使 Hcy -25%，B12 額外 -7%。
好處
- 一粒兼顧三高指標，免食三、四種補充劑
- 第三方數據支持，並非廠商自說自話
- 適合 MTHFR 基因變異者、代謝較弱長者
- 維持血管通暢，降低血栓形成風險
- 可與糖尿病藥、薄血藥等長期處方並用（建議相隔 2 小時）
臨床數據摘要：
- SIRT1 活性提升 — 超過 30%（體外 / 動物模型（Care300® 芒果萃取））
- SOD 活性提升 — 約 50%（Care300® 芒果萃取）
- 葡萄糖耐受性改善 — 顯示長期葡萄糖調節能力增強（4 週（Buchwald-Werner 2017，n=75））
- 舒張壓下降（陳年黑蒜 ABG10+） — -4.82 mmHg（特別是男性、基線舒張壓 >75 mmHg）（12 週（Valls 2022））
- 收縮壓下降（陳年黑蒜 ABG10+） — -10.2 mmHg 平均（12 週（Ried 2010））
- 三酸甘油脂下降（印度醋栗 Amla） — -34%（12 週（Upadya 2019，n=98））
- 體重 / 體脂下降（印度醋栗 Amla） — 體重 -9.9%、內臟脂肪 -20.8%（90 日（每日 1000mg，n=40））
- 同型半胱氨酸下降（甲基化 B 群） — -25%（葉酸主力）+ B12 額外 -7%（8 週（Yuan 2021，BMC Medicine））
- 收縮壓 / 舒張壓下降（納豆激酶） — 收縮壓 -5.55 mmHg、舒張壓 -2.84 mmHg（8 週（Kim 2008，n=86））
- 纖維蛋白原 / 凝血因子下降（納豆激酶） — 纖維蛋白原 -9%、第七因子 -14%、第八因子 -17%（2 個月（Hsia 2009，n=45））
注意事項
- 如有長期服用藥物，建議每 2–3 個月定期身體檢查及跟進相關指數
- 不可取代醫生處方藥物；薄血藥 / 降壓藥 / 糖尿藥患者請按醫生指示繼續服用
- 對芒果過敏者請仔細查看成分表並諮詢醫生
- 與西藥服用建議相隔約 2 小時
- 連續服用 (TODO verify long-term safety beyond brand-cited studies — source cites 8–12 週 trials)
相關知識
何謂「三高」
指高血壓、高血糖、高血脂三種最常見的慢性疾病。三者環環相扣：高血脂可能導致血管狹窄與血壓升高；血糖代謝紊亂常伴隨脂肪代謝異常。長期控制不佳會增加心肌梗塞、中風、慢性腎臟病、視網膜病變等併發症風險。
SIRT1 與 AMPK 兩大延壽軸
SIRT1 是 NAD+ 依賴的去乙醯酶，負責調控能量恆定、脂質代謝與細胞壓力耐受；AMPK 是能量感測器，透過促進脂肪氧化、葡萄糖攝取與粒線體生合成恢復代謝平衡。兩者互補：AMPK 即時降血糖、燃脂、舒張血管；SIRT1 長期提升胰島素敏感性、保護血管內皮、延緩老化。
同型半胱氨酸（Homocysteine, Hcy）
血液中的一種氨基酸代謝中間產物。正常數值 5–15 μmol/L，過高（>16）會引發氧化應激、損害血管內皮、誘導凝血、形成動脈粥樣硬化斑塊。B9（葉酸）+ B12 是「回收車間」，B6 是「廢棄車間」，缺一不可。本品採用甲基化活性 B 群，可直接被身體利用，臨床實證 8 週可使 Hcy下降 25%（葉酸主力），B12 額外再降 7%。
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